D7 moduli stabilization: the tadpole menace

D7-brane moduli are stabilized by worldvolume fluxes, which contribute to the D3-brane tadpole. We calculate this contribution in Type IIB limit of F-theory compactifications on Calabi-Yau four-folds with a weak Fano base, and able prove no-go theorem for vast swathes landscape compactifications. When genus curve dual D7 fluxes is fixed number grows, we find that D3 charge sourced grows faster than 7/16 moduli, supports Tadpole Conjecture Ref.~\cite{Bena:2020xrh}. Our lower bound induced decreases when curves stabilizing increase, does not allow rule out sliver flux configurations high-genus high-degree curves. However, argue most these have very high curvature, likely be above string scale except extremely large (and experimentally ruled out) compactification manifolds.